007 Impotence: a rare methotrexate side effect

Rare side effects of subcutaneous methotrexate therapy.

Methotrexate-induced cutaneous ulceration in 3 nonpsoriatic patients: Report of a rare side effect

H&E: hematoxylin-eosin stain MTX: methotrexate RA: rheumatoid arthritis INTRODUCTION Methotrexate (MTX) is a commonly prescribed medication in the treatment of autoimmune conditions such as rheumatoid arthritis (RA) and psoriasis. MTX is a folic acid analog and DNA synthesis inhibitor that competitively inhibits dihydrofolate reductase. Well-known side effects of MTX include diarrhea, nausea/vo...

Electrolytes imbalance: a rare side effect of piperacillin/ tazobactam therapy.

Electrolytes imbalance has been reported with the use of several antimicrobials. We report a case of severe hypokalemia secondary to piperacillin/tazobactam in a patient with normal renal function and normal serum potassium level who had presented with a fractured neck of femur. The electrolytes abnormality was corrected once piperacillin/tazobactam was stopped. To our knowledge, this is the fi...

Rifampin induced angioedema: a rare but serious side effect.

The treatment of latent tuberculosis is part of the strategy to eliminate tuberculosis (TB) in low incidence countries.1 Ten to 15 million people in the United States have latent TB, and about 300,000 Americans are treated for it each year.2 The currently recommended treatments for latent TB include using the drugs isoniazid, rifampin, and rifapentine plus isoniazid.3,4 Rifampin was discovered ...

Linezolid induced black hairy tongue: a rare side effect.

Linezolid induced black hairy tongue is a rare benign reversible side effect of linezolid therapy. We report a case of a 61 year old diabetic lady who developed thrombocytopenia and black hairy discoloration of the tongue after being prescribed linezolid for foot osteomyelitis by the orthopaedic surgeon. Patient was encouraged to practice good oral dental hygiene, advised to use a soft tooth br...